An RCSU of a service or unit of reference specializes in a technique, technology or procedure for the treatment of certain pathologies or groups of pathologies and which fulfil one or several of the criteria stipulated in Royal Decree 1302/2006, regardless of whether or not this service or unit treats other pathologies for which it does not have reference status An RCSU has to:

• Provide coverage for the entire national territory and treat patients under equal conditions regardless of their place of residence.
• Provide treatment in a multidisciplinary team: healthcare treatment, support for diagnostic confirmation, definition of therapeutic and monitoring strategies and acting as a consultant for the clinical units that regularly treat the patients in question.
• Guarantee the continuity of treatment between the stages of the patient's life (child-adult) and between healthcare levels.
• Evaluate the results.
• Training other professionals.

The following Reference Centres, Services and Units (RCSU) are currently recognized at the Hospital:

Blood diseases - Hematopoietic stem cell transplantation in children.  

Rare neuromuscular diseases, in adults. 

Sarcomas and other musculoskeletal tumours, in adults.  

Bladder exstrophy, epispadias and cloacal exstrophy, in children and adults. 

Complex glomerular diseases, in children and adults. 

Hereditary erythropathology, in children and adults. 

Complex hypothalamic pituitary pathology, in adults.

Rare diseases that occur with movement disorders (adults)

Congenital coagulopathies (children and adults)

Congenital bone marrow failure syndromes (children and adults)

Systemic autoimmune diseases (adults)           

Complex urethral reconstructive surgery in adults.

Congenital spinal cord failure syndrome